N Engl J Med 1990;322:850. 17. Features : Herbal Energy & Performance: Bronson's Korean Panax Ginseng provides 1000 MG per serving to naturally support energy and physical performance without any unwanted jitters. View abstract. Rees, W. D., Rhodes, J., Wright, J. E., Stamford, L. F., and Bennett, A. Jin, C. Y., Wang, D. L., and Fang, Z. D. [Effect of integrative Chinese and Western medicine in treating chronic urticaria and its impact on interleukin-10 and interleukin-8 in peripheral blood]. Sigurjonsdottir HA, Ragnarsson J, Franzson L, Sigurdsson G. Is blood pressure commonly raised by moderate consumption of liquorice? Dong quai grows at high altitudes in the cold, damp, mountains of China, Korea, and Japan. View abstract. [Severe hypokalemia after holidays return]. Kent UM, Aviram M, Rosenblat M, Hollenberg PF. Indian J Med Res 1993;98:69-74. View abstract. Menopause 2002;9:145-50. Minerva Med 2008;99(1):91-94. According to research, the combination of . Licorice can be used orally with Peony to treat women with Polycystic Ovary Syndrom to increase fertility; it can also treat patients with abnormal Prolactin, muscle spasms, or to reduce the pain of cancer. Select a condition to view a list of vitamins. Side effects of peony tea! Arase, Y., Ikeda, K., Murashima, N., Chayama, K., Tsubota, A., Koida, I., Suzuki, Y., Saitoh, S., Kobayashi, M., and Kumada, H. The long term efficacy of glycyrrhizin in chronic hepatitis C patients. Meta-analysis: phytotherapy of functional dyspepsia with the herbal drug preparation STW 5 (Iberogast). . Neth J Med 2005;63:149-50. Dehours E, Vall B, Roug-Bugat ME, Florent B, Bounes V, Franchitto N. Suspected hypokalaemia following liquorice ingestion on board ship. Antiviral Res 1989;11(5-6):255-261. van Uum SH. Am J Psychiatry 1994;151:617-8. View abstract. View abstract. Akamatsu, H., Komura, J., Asada, Y., and Niwa, Y. Du, J. H. and Dong, B. D. [Comparative study on clinical efficacy of using methotrexate singly or combined with total glucosides of Paeony in treating rheumatoid arthritis]. Kang, D. G., Moon, M. K., Choi, D. H., Lee, J. K., Kwon, T. O., and Lee, H. S. Vasodilatory and anti-inflammatory effects of the 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG) via a nitric oxide-cGMP pathway. Chien, C. F., Wu, Y. T., and Tsai, T. H. Biological analysis of herbal medicines used for the treatment of liver diseases. Wang H, Wei W, Wang NP, et al. Yamamoto, T., Hatanaka, M., Matsuda, J., Kadoya, H., Takahashi, A., Namba, T., Takeji, M., and Yamauchi, A. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. Okubo T, Nagai F, Seto T, et al. Some medications are changed and broken down by the liver. View abstract. Quinkler M, Stewart PM. Influence of traditional Chinese anti-inflammatory medicinal plants on leukocyte and platelet functions. View abstract. Nephrologie 1993;14(4):177-181. Astragalus may interact with medications that suppress the . Also for White Peony, the plant that is used in traditional . Meng Xiangrui is an academic researcher. The efficacy of an ayurvedic preparation of yashtimadhu (Glycyrrhiza glabra) on radiation-induced mucositis in head-and-neck cancer patients: A pilot study. Liu X, Li X, Li X, et al. It contains kojic acid, witch hazel, and licorice extracts that reduce melanin production and exfoliate . Sakamoto, S., Yoshino, H., Shirahata, Y., Shimodairo, K., and Okamoto, R. Pharmacotherapeutic effects of kuei-chih-fu-ling-wan (keishi-bukuryo-gan) on human uterine myomas. View abstract. 2019;33(1):117-29. View abstract. Sakamoto S, Kudo H, Suzuki S, et al. J Nat Prod 1980;43(2):259-269. Li G, Simmler C, Chen L, et al. and its bioactive compounds. [Study on activating blood and eliminating stasis of total paeony glycoside(TPG)]. View abstract. Anonymous. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Comparative study of bioactive constituents in crude and processed Glycyrrhizae radix and their respective metabolic profiles in gastrointestinal tract in vitro by HPLC-DAD and HPLC-ESI/MS analyses. J Pharm Pharmacol 2003;55:1275-82. Electronic Code of Federal Regulations. View abstract. View abstract. Side effects, toxicity, and interactions. J Nutr 2001;131:1471-8. Peony might change how quickly the liver breaks down these medications. A., Torres Murillo J., and Calderon de la Barca Gazquez J. M. [Acute rhabdomyolysis and tetraparesis secondary to hypokalemia due to ingested licorice]. Effect of Japanese Angelica root and peony root on uterine contraction in the rabbit in situ. Sheehan MP, Atherton DJ. Davis EA, Morris DJ. Yoon JY, Cha JM, Hong SS, et al. A comparison of carbenoxolone sodium and deglycyrrhizinated liquorice in the treatment of gastric ulcer in the ambulant patient. View abstract. Therapeutic Research Faculty 2020. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Allergic contact dermatitis to Glycyrrhiza inflata root extract in an anti-acne cosmetic product. Brouwers, A. J. and van der, Meulen J. If you take birth control pills along with peony, use an additional form of birth control such as a condom. Eriksson JW, Carlberg B, Hillom V. Life-threatening ventricular tachycardia due to liquorice-induced hypokalemia. J Steroid Biochem Mol Biol 1994;49:81-5. Medicine (Baltimore) 2019;98(35):e16601. View abstract. Alt Med Rev 2001;6:495-9. Journal of Clinical Therapeutics Medicine. Schweiz Med Wochenschr 2-26-1977;107(8):276-279. J Clin Psychopharmacol 2016;36(6):572-9. J Clin Psychopharmacol 1997;17(3):234-235. Taking peony along with estrogen might increase the effects and side effects from estrogen. 2000;20(1):38-41. 2014 Jun;23(3):189-92. Licorice can decrease how quickly the body breaks down corticosteroids. J Intern Med 1999;245:307-10. Muscle cramps.Early research suggests that taking a specific combination of peony and licorice (Shakuyaku-kanzoh-to) might ease muscle cramps in people with liver cirrhosis and in people undergoing hemodialysis. Anesth Analg. Anon. Gulf J Oncolog 2021;1(37):42-47. Effects of paeoniflorin on the cerebral infarction, behavioral and cognitive impairments at the chronic stage of transient middle cerebral artery occlusion in rats. Licorice or Mulethi, also known as "Sweetwood", is an effective and potent medicinal herb. Aoki, F., Nakagawa, K., Kitano, M., Ikematsu, H., Nakamura, K., Yokota, S., Tominaga, Y., Arai, N., and Mae, T. Clinical safety of licorice flavonoid oil (LFO) and pharmacokinetics of glabridin in healthy humans. View abstract. Yu C, Fan X, Li Z, Liu X, Wang G. Efficacy and safety of total glucosides of paeony combined with acitretin in the treatment of moderate-to-severe plaque psoriasis: a double-blind, randomised, placebo-controlled trial. Acute myopathy associated with chronic licorice ingestion: reversible loss of myoadenylate deaminase activity. Coloclyster of Red Peony Root Granules Alleviates Moderately Severe Acute Pancreatitis: A Double-Blinded, Placebo-Controlled, Randomized Clinical Trial. View abstract. View abstract. View abstract. 2010;16(4):216-218. Additional reporting by Meghan De Maria. We currently have no information for PEONY overview. B., and Zhang, Z. J. View abstract. A double-blind, randomized, placebo-controlled, multicenter trial. View abstract. Ma, X. F. [Experimental and clinical studies on the treatment of pulmonary heart disease and pulmonary hypertension with Paeonia lactiflora]. View abstract. A randomized, double-blind comparison of licorice versus sugar-water gargle for prevention of postoperative sore throat and postextubation coughing. Licorice can cause serious side effects if you take too much of it or use it for too long. Abe K, Higurashi T, Takahashi M, et al. View abstract. Cancer 1997;79(8):1494-1500. View abstract. Li J, Fan X, Wang Q. Hypertensive crisis with 2 target organ impairment induced by glycyrrhizin: a case report. Martin, M. D., Sherman, J., van der Ven, V., and Burgess, J. One of its most known effects is the induction of hypertension, and it can induce what appears to be pseudohyperaldosteronism, due to glycyrrhetinic acid, the main active component of the root. Yang DG. View abstract. Elinav E, Chajek-Shaul T. Licorice consumption causing severe hypokalemic paralysis. Some possible side effects with oral use include rash, itching, nasal symptoms, or stomach discomfort, but these are uncommon. Yoshida S, Takayama Y. Licorice-induced hypokalemia as a treatable cause of dropped head syndrome. Am J Chin Med 1992;20(3-4):313-317. A 2020 review found that licorice root extract can help reduce the growth of . Licorice might decrease the effects of warfarin. J Endocrinol Invest 2003;26:646-50. View abstract. J Hepatol 1994;21:601-9. Yamada, K., Kanba, S., Yagi, G., and Asai, M. Effectiveness of herbal medicine (shakuyaku-kanzo-to) for neuroleptic-induced hyperprolactinemia. Z Kardiol 1991;80(6):389-391. Madisch A, Melderis H, Mayr G, et al. White peony ( bai shao in Chinese) is root without any bark, while red peony . Amaryan G, Astvatsatryan V, Gabrielyan E, et al. Some medications are moved in and out of cells by pumps. View abstract. Baykul, T., Alanoglu, E. G., and Kocer, G. Use of Ankaferd Blood Stopper as a hemostatic agent: a clinical experience. View abstract. Br J Dermatol 1992;126:179-84. Nephol Dial Transplant 1999;14:218-20. Part 182 -- Substances Generally Recognized As Safe. There are studies with assisted nutrients to expedite healing and mitigate side effects of hormone imbalances associated with IVF/IUI discussed below. [RETRACTED]. Fortschr.Med 7-30-1992;110(21):395-398. Kimura Y, Okuda H, Okuda T, and et al. 2016 Oct;39:314-319. doi: 10.1016/j.intimp.2016.08.006. 2020;16(3):458-462. 2005 - 2023 WebMD LLC. Petramfar P, Hajari F, Yousefi G, Azadi S, Hamedi A. Efficacy of oral administration of licorice as an adjunct therapy on improving the symptoms of patients with Parkinson's disease, A randomized double blinded clinical trial. J Pharmacobiodyn 1983;6:153-60. . Eur J Dermatol. Peony might block chemicals that can cause pain and swelling . View abstract. Luo, Y. G., Liu, Y. Q., and Hu, J. Gardner Z, McGuffin M. Boca Raton, FL: CRC Press, 2013. *. Traditional Chinese medicines Wu Wei Zi (Schisandra chinensis Baill) and Gan Cao (Glycyrrhiza uralensis Fisch) activate pregnane X receptor and increase warfarin clearance in rats. Astragalus may be safe when used orally and appropriately. Postgrad Med J 2003;79:115-6.. View abstract. This can be severe. Fiore, C., Eisenhut, M., Krausse, R., Ragazzi, E., Pellati, D., Armanini, D., and Bielenberg, J. Antiviral effects of Glycyrrhiza species. View abstract. View abstract. West J Med 1997;167(3):184-185. Koo YK, Kim JM, Koo JY, et al. Antiviral Res 1987;7(3):127-137. When eaten in large quantities, black licorice can cause serious health issues. Bocker, D. and Breithardt, G. [Induction of arrhythmia by licorice abuse]. Feng ZT, Xu J, He GC, Cai SJ, Li J, Mei ZG. Mechanisms by which Hange-shashin-to reduces prostaglandin E2 levels. Kinoshita T, Maruyama K, Yamamoto N, Saito I. Effects of the licorice extract against tumor growth and cisplatin-induced toxicity in a mouse xenograft model of colon cancer. [Protective mechanism of Salvia miltiorrhiza and Paeonia lactiflora for experimental liver damage]. J Med Liban 2012;60(2):117-119. View abstract. Burgess, J. Zhang W, Leonard T, Bath-Hextall F, et al. The dose of your warfarin might need to be changed. View abstract. Biol Pharm Bull. Effects of Paeoniae Radix, a traditional Chinese medicine, on the pharmacokinetics of phenytoin. Motherwort, Peony, Dong Quai, Lady's Mantle, Licorice, and Rose, Fennel, Alfalfa. Yuan, H. N., Wang, C. Y., Sze, C. W., Tong, Y., Tan, Q. R., Feng, X. J., Liu, R. M., Zhang, J. . About Dr.Cope. Licorice extract inhibits the production of tyrosinase, in turn inhibiting the production of dark spots. Nussbaumer, U., Landolt, M., Rothlisberger, G., Akovbiantz, A., Keller, H., Weber, E., Blum, A. L., and Peter, P. [Postoperative stress hemorrhage: ineffective prevention with pepsin inhibitor and deglycyrrhizinized licorice extract. Gut 1973;14(9):711-715. It might also decrease the effects of birth control pills. Caradonna, P., Gentiloni, N., Servidei, S., Perrone, G. A., Greco, A. V., and Russo, M. A. View abstract. View abstract. Be sure to have your blood checked regularly. Costa, A., Moises, T. A., Cordero, T., Alves, C. R., and Marmirori, J. Double-blind, placebo-controlled, randomized, pilot clinical trial of ImmunoGuard--a standardized fixed combination of Andrographis paniculata Nees, with Eleutherococcus senticosus Maxim, Schizandra chinensis Bail. Eur J Pharmacol 11-7-2005;524(1-3):111-119. World J Gastroenterol 2005;11:2124-9. . 2010 Nov;35(10):1587-93. The herb licorice may lower warfarin levels and can add to digoxin's effects. Kitagawa, I., Chen, W. Z., Hori, K., Harada, E., Yasuda, N., Yoshikawa, M., and Ren, J. The roots are commonly used in Traditional Chinese Medicine (TCM) for many purposes. Hataya Y, Oba A, Yamashita T, Komatsu Y. Hyponatremia in an elderly patient due to isolated hypoaldosteronism occurring after licorice withdrawal. Licorice root and white peony for PCOS. View abstract. Teelucksingh S, Mackie AD, Burt D, McIntyre MA, Brett L, Edwards CR. 2020;247:112226. View abstract. Hsiang, C. Y., Hsieh, C. L., Wu, S. L., Lai, I. L., and Ho, T. Y. Inhibitory effect of anti-pyretic and anti-inflammatory herbs on herpes simplex virus replication. Li C, Wang ZB. Z. Bannister, B., Ginsburg, R., and Shneerson, J. Cardiac arrest due to liquoriceinduced hypokalaemia. Neurology 2010;75(21):1939-1941. View abstract. 2020 Dec;58(1):352-356. View abstract. 2013 Jun;22(2):173-8. 2020;45(2):257-264. Little is known about whether it's safe to use licorice root while breastfeeding. Back to the Blog. Hasegawa, J., Suyama, Y., Kinugawa, T., Morisawa, T., and Kishimoto, Y. Echocardiographic findings of the heart resembling dilated cardiomyopathy during hypokalemic myopathy due to licorice-induced pseudoaldosteronism. 2019;18(Suppl1):291-301. [Clinical observations on the treatment of the gestational hypertension syndrome with Angelica and Paeonia powder]. View abstract. View abstract. Heidemann HT, Kreuzfelder E. Hypokalemic rhabdomyolysis with myoglobinuria due to licorice ingestion and diuretic treatment. Effect of Shakuyaku-kanzo-to (Tsumura TJ-68) on muscle cramps accompanying cirrhosis in a placebo-controlled double-blind parallel study. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Ruiz-Granados, E. S., Shouls, G., Sainsbury, C., and Antonios, T. A salty cause of severe hypertension. Bell ZW, Canale RE, Bloomer RJ. View abstract. View abstract. Kinoshita, H., Okabayashi, M., Kaneko, M., Yasuda, M., Abe, K., Machida, A., Ohkubo, T., Kamata, T., and Yakushiji, F. Shakuyaku-kanzo-to induces pseudoaldosteronism characterized by hypokalemia, rhabdomyolysis, metabolic alkalosis with respiratory compensation, and increased urinary cortisol levels. The effects of dietary licorice flavonoid oil supplementation on body balance control in healthy middle-aged and older Japanese women undergoing a physical exercise intervention: a randomized, double-blind, placebo-controlled trial. J Biol Response Mod 1985;4:551-84. View abstract. Anesth Analg 2009;109(1):77-81. Licorice is an herb that grows in parts of Europe and Asia. He X, Xing D, Ding Y, et al. Liang, R., Chen, M. R., and Xu, X. J Infect.Chemother. J Altern Complement Med 2009;15(4):439-443. View abstract. Wang Y, Ma R. [Effect of an extract of Paeonia lactiflora on the blood coagulative and fibrinolytic enzymes]. Black licorice can have serious side effects when eaten in large amounts. View abstract. O'Connell K, Kinsella J, McMahon C, Holian J, O'Riordan S. Posterior reversible encephalopathy syndrome (PRES) associated with liquorice consumption. 6. Biol Pharm Bull. Black licorice contains a compound that comes from licorice root that can lower your potassium levels. View abstract. Part 2: Effect of glycyrrhizic acid on the course of illness]. Fan ZJ, Liu JM, Li XX, et al. Aliment Pharmacol Ther 2004;20:1279-87. Fitoterapia 2004;75:45-9.. View abstract. Riv Patol Nerv Ment 1983;104(4):179-183. Das SK, Das V, Gulati AK, and et al. This versatile anti-inflammatory plant can benefit digestive issues, hormone health, and skin health as well as helping ease problems with menstruation and menopause. A., van Dokkum, W., and Savelkoul, T. J. Glycyrrhizic acid: the assessment of a no effect level. View abstract. View abstract. View abstract. Am J Chin Med 2001;29(3-4):459-467. Some birth control pills contain estrogen. View abstract. But the potential side effects are real enough. Hossain, M. S., Takimoto, H., Hamano, S., Yoshida, H., Ninomiya, T., Minamishima, Y., Kimura, G., and Nomoto, K. Protective effects of hochu-ekki-to, a Chinese traditional herbal medicine against murine cytomegalovirus infection. Licorice is an herb that grows in parts of Europe and Asia. Some sources claim that it's contraindicated during pregnancy . Kormann R, Languille E, Amiot HM, Hertig A. A., Braun, T. M., and Jacobson, J. J. View abstract. Wang W, Tian DD, Zheng B, et al. Lipids Health Dis 2011;10:29. (Doses up to 60 grams daily for up to 4 months have been used without reported adverse effects.) Clinical application of compound Glycyrrhizin tablets in the treatment of patients with Simplex Henoch-Schonlein Purpura and its effect on immune function. How Much Is Too Much? View abstract. A controlled trial of traditional Chinese herbal medicine in Chinese patients with recalcitrant atopic dermatitis. View abstract. Some believe it may also increase estrogen and prolactin levels in women, though more research is warranted. Let's take a look at the forms, uses, and side effects of . View abstract. Man SC, Li XB, Wang HH, et al. View abstract. Adjuvant role of a new emollient cream in patients with palmar and/or plantar psoriasis: a pilot randomized open-label study. Saeedi, M., Morteza-Semnani, K., and Ghoreishi, M. R. The treatment of atopic dermatitis with licorice gel. Zhong.Xi.Yi.Jie.He.Za Zhi. View abstract. Yamashiki, M., Nishimura, A., Suzuki, H., Sakaguchi, S., and Kosaka, Y. View abstract. It's not suggested to take St. John's wort if you take blood thinners. 2020;383(13):1263-1275. [Effect of fu-zheng qu-xie on gastric disease infected with Campylobacter pyloridis]. van Rossum, T. G., Vulto, A. G., Hop, W. C., Brouwer, J. T., Niesters, H. G., and Schalm, S. W. Intravenous glycyrrhizin for the treatment of chronic hepatitis C: a double-blind, randomized, placebo-controlled phase I/II trial. Jafari Z, Emtiazy M, Sohrabvand F, et al. Effects of low-dose liquorice alone or in combination with hydrochlorothiazide on the plasma potassium in healthy volunteers. Int Urol Nephrol. Oh, G. S., Pae, H. O., Choi, B. M., Lee, H. S., Kim, I. K., Yun, Y. G., Kim, J. D., and Chung, H. T. Penta-O-galloyl-beta-D-glucose inhibits phorbol myristate acetate-induced interleukin-8 [correction of intereukin-8] gene expression in human monocytic U937 cells through its inactivation of nuclear factor-kappaB. View abstract. Hinoshita F, Ogura Y, Suzuki Y, et al. Messier, C., Epifano, F., Genovese, S., and Grenier, D. Licorice and its potential beneficial effects in common oro-dental diseases. Akbari N, Asadimehr N, Kiani Z. Fujisawa, Y., Sakamoto, M., Matsushita, M., Fujita, T., and Nishioka, K. Glycyrrhizin inhibits the lytic pathway of complement--possible mechanism of its anti-inflammatory effect on liver cells in viral hepatitis. Hsiu, S. L., Lin, Y. T., Wen, K. C., Hou, Y. C., and Chao, P. D. A deglucosylated metabolite of paeoniflorin of the root of Paeonia lactiflora and its pharmacokinetics in rats. View abstract. Chinese herbal medicine for atopic eczema. Yang F, Qi X, Du Y, et al. Constituent properties of licorices derived from Glycyrrhiza uralensis, G. glabra, or G. inflata identified by genetic information. Not too many side effects of peony tea that we need to worry about. A pilot study. View abstract. Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus. Thom E and Wollan T. A controlled clinical study of kanjang mixture in the treatment of uncomplicated upper respiratory tract infections. Deglycyrrhizinated liquorice in duodenal ulcer. Huang, W. W., Wang, M. Y., Shi, H. M., Peng, Y., Peng, C. S., Zhang, M., Li, Y., Lu, J., and Li, X. Antiviral Res 2003;59(1):41-47. View abstract. Oral Dis 2012;18(1):32-39. The combination of Licorice and Peony has been used in TCM for centuries and now used extensively in western herbal medicine for ovarian cysts and PCOS. J Peripher.Nerv.Syst. Effect of Shakuyaku-kanzo-to (Tsumura TJ-68) on muscle cramps accompanying cirrhosis in a placebo-controlled double-blind parallel study. Ai, M., Yamaguchi, T., Odaka, T., Mitsuhashi, K., Shishido, T., Yan, J., Seza, A., and Saisho, H. Objective assessment of the antispasmodic effect of shakuyaku-kanzo-to (TJ-68), a Chinese herbal medicine, on the colonic wall by direct spraying during colonoscopy. But not everyone will have the side . Lapi F, Gallo E, Bernasconi S, et al. Am J Epidemiol 2001;153:1085-8. As I've all but cut out alcohol, I've tended to drink this tea before going to bed and sometimes during the day. View abstract. View abstract. It has an effect similar to aldosterone. J Hum Hypertens 2001;15:549-52. A controlled trial of traditional Chinese medicinal plants in widespread non-exudative atopic eczema. View abstract. Am J Chin Med 2003;31:445-53. . Another type of licorice, called DGL or deglycyrrhizinated licorice, does not seem to have the same side effects and is sometimes used to treat peptic ulcers, canker sores, and reflux (GERD). Fang, J. Y. View abstract. Evid Based Complement Alternat Med. 2000;20(3):173-175. Rackova, L., Jancinova, V., Petrikova, M., Drabikova, K., Nosal, R., Stefek, M., Kostalova, D., Pronayova, N., and Kovacova, M. Mechanism of anti-inflammatory action of liquorice extract and glycyrrhizin. Licorice root contains glycyrrhizin, which can cause side effects when eaten in large amounts. Peony (Paeonia lactiflora) is an herb. Red Peony Root (Paeniae Rubra Radix) 8 g Myrrh (Myrrha) . An unusual cause of hypokalemic paralysis: chronic licorice ingestion. J Pharmacol Exp Ther 2006;316:1369-77. 1993;13(10):591-3, 579. Peony and Licorice is a safe and gentle yet powerful formula that is famous for its ability to build blood and balance menstrual cycles. 2 in the perioperative stage of laparoscopic cholecystectomy]. Medically reviewed by Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT By Kirsten Nunez on October 16, 2020. "It contains liquiritin, an active compound that helps to disperse and remove existing melanin in the skin," explains Chwalek. Pfeifer BL, Pirani JF, Hamann SR, Klippel KF. View abstract. Association of emblica, licorice and belides as an alternative to hydroquinone in the clinical treatment of melasma. View abstract. A man in Massachusetts died after eating too much black licorice, which contains a compound known to be toxic in large doses, according to a new report. View abstract. View abstract. Armanini, D., Mattarello, M. J., Fiore, C., Bonanni, G., Scaroni, C., Sartorato, P., and Palermo, M. Licorice reduces serum testosterone in healthy women. View abstract. CJEM 2009;11(1):94-96. Licorice that has the active ingredient of glycyrrhiza can have serious side effects. N Engl J Med 1990;322:849-50. Title 21. View abstract. Mumoli, N. and Cei, M. Licorice-induced hypokalemia. Izv Akad Nauk Ser Biol 1997;2:235-7. . Effects of Paeonia lactiflora root extracts on the secretions of monocyte chemotactic protein-1 and -3 in human nasal fibroblasts. Phytother Res 2012;26(9):1381-1384. View abstract. 2020. View abstract. J Clin Periodontol 1991;18(3):210-212. It shows a wide range of biological and pharmacological activities, including anti-inflammatory and immune regulatory actions. A dual investigation of the effect of dietary supplementation with licorice flavonoid oil on anthropometric and biochemical markers or health and adiposity. View abstract. View abstract. Combined Lifestyle and Herbal Medicine in Overweight Women with Polycystic Ovary Syndrome (PCOS): A Randomized Controlled Trial. A Rutgers expert discusses how eating black licorice can affect your health. View abstract. View abstract. Taking licorice along with "water pills" might make potassium levels drop too low. Effect of orally administered shao-yao-gan-cao-tang (Shakuyaku-kanzo-to) on muscle cramps in maintenance hemodialysis patients: a preliminary study. Gallacher SD, Tsokolas G, Dimitropoulos I. Liquorice-induced apparent mineralocorticoid excess presenting in the emergency department. The Potential Benefits and Side Effects of the White Peony Root. View abstract. Ann Clin Biochem 2007;44(Pt 4):397-399. Am J Chin Med 2003;31:445-53. . Zhou Y, Jin L, Kong F, et al. Clinical reduction of S. mutans in pre-school children using a novel liquorice root extract lollipop: a pilot study. Zhang XH, Lowe D, Giles P, et al. Efficacy of traditional Chinese herbal therapy in adult atopic dermatitis. Heavy consumption of licorice during pregnancy has been associated with premature birth and health problems in the child. Armanini D, Bonanni G, Palermo M. Reduction of serum testosterone in men by licorice. Armanini D, Lewicka S, Pratesi C, et al. View abstract.