how long do venofer side effects last

Keep out of reach of children. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. If youre wondering how longside effectslast, youll be happy to know they can last just a few hours. What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). Injectafer may not be right for you if you have certain medical conditions or other factors affecting your health. There are currently no generic forms of either drug. Very bad and sometimes deadly allergic side effects have rarely happened. Injectafer isnt a medication that youll take regularly on a schedule. If you have questions about using Injectafer in a child, talk with your doctor. This medicine may cause serious types . Throw away unused or expired drugs. Discuss the risks and benefits with your doctor. An example of a drug interaction that many people are not aware of isgrapefruitjuice and statins. In the US - Call your doctor for medical advice about side effects. For more information about Injectafers approved uses, see the section Injectafer uses below. "That's why it's so . Venofer (iron sucrose) injection, USP is an intravenous (IV) form of iron, which is a key ingredient for making new red blood cells. Symptoms of a severe allergic reaction can include: Because of the risk of allergic reaction with Injectafer, your healthcare professional will monitor you for at least 30 minutes after you get each dose of the drug. US residents can call their local poison control center at 1-800-222-1222. If either is present, do not use the liquid. Talk with your doctor. Vomiting. You may also report side effects at https://www.fda.gov/medwatch. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. These side effects can range from being mild to severe. For people with certain medical implants, such as pacemakers, an MRI may pose an . Learn how to store and discard medical supplies safely. Drug class: Iron products. Serious side effects from Injectafer arent common, but they can occur. The insurance company will review the prior authorization request and decide if the drug will be covered. Its responsible for carrying oxygen throughout your body. This is why they have a programcalledMedWatchthat encourages Americans to report adversereactions. Injectafer is approved to treat iron deficiency anemia (IDA). Injectafer can be exposed to temperatures between 59F to 86F (15C to 30F) for a short period of time. Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. SIDE EFFECTS: Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. Your doctor will determine the best dosage to fit your needs. The body cannot metabolize such a high dose fast enough, so it ends up affecting a part of the body it wasnt intended to, such as the stomach. You may need extra iron because of blood loss during kidney dialysis. Many people using this medication do not have serious side effects. . Its not currently available in generic form. You may report side effects to the FDA at 1-800-332-1088. Symptoms of overdosage include drowsiness, mental confusion, dizziness, diarrhea and vomiting etc. The infusion concentration should not be less than 2 mg of Injectafer per mL of solution. * Feraheme has a boxed warning for this side effect. Use Venofer as ordered by your doctor. Injectafer can cause low blood levels of phosphorus, which is a condition called hypophosphatemia. You may report side effects to FDA at 1-800-FDA-1088. If you have any of these health problems: Too much iron in your body or anemia from a cause other than low iron. XAO$$d|0tX1`Q$Il#FBm}{#h!/;[bOvvg7 ?tMl7/+wya^,~PA}6&Ftb19OeJ6-a3acKjcpkeGq+7/nO AJJ:Okyfp;xw|]McmK?9"t0m%. If the underlying cause of your anemia isnt addressed, theres a chance your anemia could come back after Injectafer treatment. Brand-name medications usually cost more than generics. Both Injectafer and Feraheme belong to a class of medications known as iron replacement products. Learn about uses, cost, how it works, and more. Do not share your drugs with others and do not take anyone else's drugs. Call your doctor right away if youre having a severe allergic reaction to Injectafer, even if youve had doses of the drug in the past without any problems. If you have any questions about Venofer, please talk with your doctor, nurse, pharmacist, or other health care provider. If you have questions about side effects, call your doctor. Theyll likely have you stop taking the pills while youre using Injectafer. Your doctor will be able to see how Venofer is working by reviewing your blood tests. weakness. (IV iron is absorbed by the body more rapidly than oral iron.) Injectafer contains the active drug ferric carboxymaltose, while Venofer contains the active drug iron sucrose. This website is intended for use by US healthcare professionals only. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Details. Dr. Brandon ColbyMDis a US physician specializingin the personalized prevention of disease through the use of genomic technologies. Data on file, American Regent, Inc. 1. cough. In clinical studies, people who took Injectafer had their hemoglobin level improve as early as 35 days after receiving treatment. There isnt a known interaction between Injectafer and alcohol. Consult the product instructions and your pharmacist for storage details. You would receive 15 mg of Injectafer per kilogram of body weight for each of your two doses. People who weigh less than 110 lb (about 50 kg) will receive two separate Injectafer doses of 15 mg/kg of body weight. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics(ACMG), an Associate of the American College of Preventive Medicine(ACPM), and a member of the National Society of Genetic Counselors(NSGC). Do not exceed 1,500 mg of iron per dosing course. Keep in mind that the risk of certain pregnancy-related problems can be increased if iron deficiency anemia (IDA) is left untreated. A delayed reaction can occur in two different ways: It can happen hours or days after you receive a drug, or it can happen after a second (or later) dose of a drug. Storage Condition Store in a cool and dry place protected from light. Seriousside effectsshould be reported to a physician and/orPharmDfor medical advice. 2022 American Regent, Inc.PP-VE-US-0016 (v6.0)1/2022, Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your organs and tissues through hemoglobin, If you or your child has been prescribed Venofer, its based on your blood work, which shows how many red blood cells you have and whether you have enough iron in your blood cells, If you are iron deficient, raising your iron levels can help increase your hemoglobin levels, Treating your anemia may help prevent future health problems, Over time, untreated IDA can cause heart problems; if you already have heart problems, it can make those problems worse, Venofer is given intravenously (through an IV) and You should not receive Venofer if you have ever had an allergic reaction to an iron injection, or if you have iron overload (the buildup of excess iron) or hemochromatosis. (A medication class is a group of medications that work in a similar way.). Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Although a single administration of FCM frequently causes transient hypophosphatemia, a 2016 study showed that repeated treatment with FCM is associated with a high risk of developing severe and prolonged hypophosphatemia and should therefore be monitored. (A medication class describes a group of drugs that work in the same way.). Common MRI side effects include dizziness, anxiety, headache, nausea, hearing loud noises, and feeling chilled or hot in the MRI scanner. Keep all medications away from children and pets. It can be given as a slow injection over 2 to 5 minutes or as an infusion. Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness. Once inside your body, ferric carboxymaltose releases iron into your system. If you have more questions about how Injectafer will affect your anemia, talk with your doctor. Injectafer and Feraheme can cause very similar side effects, but some different ones as well. If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. You should always consult your doctor or another healthcare professional before taking any medication. If youre interested in finding an alternative to Injectafer, talk with your doctor. Injectafer is available only as a brand-name medication. For instance, those who are taking other medications or supplements as part of home remedies may continue to suffer from the ill effects of their new medication because they dontinteract. The infusion will take between 15-30 minutes if it is given in. Mental healthdisorders like depression may requireantidepressantsto treat. Tell your doctor about the allergy and what signs you had. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. For more information about taking Injectafer during pregnancy, see the section Injectafer and pregnancy above. Injectafer should be stored between 68F to 77F (20C to 25C). We cancelled my 5th because of the reaction. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Venofer is injected. Iron infusion side effects vary depending on which form is being used. Call your doctor for medical advice about side effects. And this type of reaction is possible even if you didnt have a reaction to your first dose of the drug. Version: 7.01. And this person had gotten their first dose of the drug without having an allergic reaction. <> They can recommend if this is safe for you to do. Injectafer and Feraheme are both brand-name drugs. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. Generics tend to cost less than brand-name drugs. Venofer (iron sucrose injection, USP) Rx Only DESCRIPTION Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. With anemia, you have a low level of red blood cells (RBCs) in your body. chills difficulty with moving ear congestion or pain flushed, dry skin fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. Most people will metabolize medication by half every time it circulates the body. Infusion times range from less than 20 minutes to up to 4 hours. Together, they can recommend ways to help you manage a body weight thats healthy for you. Some people may also experience skin irritation from the adhesive tape and other medical equipment used during the procedure. The time it takes to infuse Venofer (iron sucrose) depends on your age, if you're on dialysis, and the type of dialysis you need. Your dosage and length of treatment are based on your medical condition, age, and response to treatment. Joint pain. But you kidneys need iron in order to make EPO. No, you most likely wont take Injectafer long term. wAd**CgI%"nn{Oa[q{r5 Depending on your anemia symptoms, your weight changes may be different than those described here. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). Injectafer contains the active drug ferric carboxymaltose. TheNational Instituteof Health (NIH) and the U.S. Food andDrug Administration(FDA) monitor theside effectsof new and approved medications to ensure safety. Depending on your doctors instructions and Low iron saturation, or iron deficiency, has various possible causes. Its caused by your body not having enough iron, which is needed to make hemoglobin. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Administer Venofer in 3 divided doses, given by slow intravenous infusion, within a 28 day period: 2 infusions each of 300 mg over 1.5 hours 14 days apart followed by one 400 mg infusion over 2.5 hours 14 days later. This information is not specific medical advice and does not replace information you receive from the healthcare provider. But the length of time that this may take varies from person to person. Your doctor will do laboratory tests to monitor your response. Review our medical disclaimer. In Canada - Call your doctor for medical advice about side effects. If this happens to you, your doctor may recommend that you receive another treatment course of Injectafer. Injectafer isnt available in a generic form. Many patients with kidney disease cannot get enough iron from food and require injections. Other drugs may interact with iron sucrose, including prescription and over-the-counter medicines, vitamins, and herbal products. Last updated August 20, 2020. Check with your pharmacist. For example: Say you weigh 105 pounds (about 48 kilograms). Venofer (iron sucrose) can also be mixed in a saline solution and given through an IV over a longer time. Theyll do this by checking certain blood tests. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. Most people do not know how long theirside effectswill last until they go through them. Hemoglobin is a protein thats found inside your red blood cells. In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. The iron released by this drug does pass into human breast milk. Tell all of your health care providers that you take Venofer. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Keep all regular medical and laboratory appointments. Its not known how often people taking a treatment other than Injectafer had diarrhea. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Venofer. Treatment with Venofer injections can make it harder for your body to absorb iron medications you take by mouth. Taking a larger dose of LSD can extend the duration of the trip, but generally, the main effects of LSD don't tend to last any longer than 12 hours. Ask your doctor or healthcare provider if Venofer is the right choice for you. Details. Available for Android and iOS devices. For example, if someone takes 100 mg of a drug, only half of it will be in the bloodstream in a couple ofhours. Also tell them about any vitamins, herbs, and supplements you use. For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. If your symptoms or health problems do not get better or if they become worse, call your doctor. If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. SIDE EFFECTS: In adult patients, the most common side effects (2%) include diarrhea, upset stomach, throwing up, headache, dizziness, hypotension, pruritus (itching), pain in extremity, arthralgia (joint pain), back pain, muscle cramp, injection site reactions, chest pain and peripheral edema (swelling). Some people are simply allergic to an active ingredient in the medication, so the body responds undesirably. This medication is given by injection into a vein as directed by your doctor. <> In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). Iron sucrose can make it harder for your body to absorb iron medications you take by mouth. You can also write a reminder on your calendar. Other side effects include: Common (may affect up to 1 in 10 users) Temporary taste changes (especially metallic taste) Low blood pressure or high blood pressure. Then your body uses that iron to make hemoglobin and RBCs. Serious side effects, which are explained in more detail below in Side effect details, include: You may wonder how often certain side effects occur with this drug. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction. There are 2 tests that your doctor will likely Injectafer and Venofer have different approved uses, but theyre both used to treat IDA in people with CKD. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. This includes people who: Usually, hypophosphatemia doesnt cause symptoms. With a delayed reaction, your body reacts to a drug that youve been exposed to in the past without having a reaction. The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. Once you have waited for 30 minutes after the injection, you may go home, providing you are feeling well. If you have iron deficiency anemia (IDA), consuming moderate amounts of alcohol may be safe, if your doctor tells you its OK. (With IDA, you have a low level of red blood cells thats caused by not having enough iron.). Some products that may interact with this drug include: vitamin products, other iron-containing products. We comply with the HONcode standard for trustworthy health information. Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. Iron sucrose can harm an unborn baby if you have a severe reaction to this medicine during your second or third trimester. If youre not sure if youll need to get prior authorization for Injectafer, contact your insurance company. Do not use Injectafer in people with a history of hypersensitivity reactions to Injectafer or any components of the drug product. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Their medical staff can help you set up another time to receive your Injectafer dose. As with most drugs, some people can have an allergic reaction after taking Injectafer. This could happen because Injectafer helps increase their hemoglobin levels, but it doesnt address the underlying cause of their anemia. Knowing how longside effectslast can help with the decision on whether to use a particulardrug. Common Venofer side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting, diarrhea; muscle or joint pain, back pain; pain or swelling in an arm or leg; itching; or bruising or irritation where the medicine was injected. To learn about other mild side effects, talk with your doctor or pharmacist, or see Injectafers package insert. Theyll recommend how to manage your condition. It is very important that your doctor check you closely while you are receiving this medicine. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Venofer only for the indication prescribed. However, some people may have weight changes as they have improvement in their anemia, which Injectafer is used to treat. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. endobj Generic name: iron sucrose (injection) [EYE-urn-SOO-krose] Serious side effects should be reported to a physician and/or PharmD for medical advice. Injectafer is indicated to treat iron deficiency anemia (IDA) in adults who meet one of the following criteria: Injectafer is administered intravenously, either by intravenous (IV) infusion or as an undiluted, slow IV push. These side effects may include constipation and diarrhea. However, there has been a report of delayed allergic reaction in someone receiving a second dose of Injectafer. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Learn more about the types of tests and treatment. Things to remember when you fill your prescription. There are different types of anemia, but IDA is the most common type. The signs and symptoms of anaphylaxis include dizziness or fainting, skin flushing and itchiness, difficulty breathing, rapid heart rate, low blood pressure and sudden anxiety. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. Orofer S 100 Injection 1 Injection in 1 Packet 286 301 5% off. Potential side effects that are usually mild may include, but are not limited to: Headache Nausea Dry Mouth Stomachache Dizziness Diarrhea Constipation These side effects may not impact life too much and may only be temporary. Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. If you have questions about the blood tests youll need to have done to monitor your anemia, talk with your doctor. Below are examples of these side effects. Most of these side effects may go away within a few days or a couple of weeks. Examples of these side effects include dizziness and nausea. Tell your caregivers right away if you have: problems with your dialysis vein access point; high blood pressure - severe headache, blurred vision, pounding in your neck or ears; low blood pressure - a light-headed feeling, like you might pass out; or. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. Which tests can diagnose iron deficiency anemia? While the side effects that occur during treatment with these drugs are increasingly well-cataloged, the long-term side effects that may result from receiving these drugs are only beginning to be studied. If you notice other effects not listed above, contact your doctor or pharmacist. treatment schedule in further detail. With IV infusion, the drug is given as a slow drip into your vein over a period of time. This is only a brief summary of general information about this medicine. They have been a god send. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. FG Trade/E+ sia Getty Images If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. A healthcare provider will give you this injection. Injectafer comes as a liquid thats given by either intravenous (IV) infusion or slow IV injection. Precautions. A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. But in some people, Injectafer can cause symptoms of hypophosphatemia to occur. 2005 - 2023 WebMD LLC. Notify your healthcare provider of any irritation at the injection site. Evenbirth controlcan lead to severeside effectslike bloodclots. Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: And Feraheme is approved for use in adults who have CKD who may or may not need dialysis. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. And theyll recommend how soon after starting the drug you need to have this level checked. People with IDA have low blood levels of hemoglobin. Here's some detail on certain side effects this drug may cause. (Hemoglobin is a protein thats found in red blood cells.). IQVIA [NSP Audit from MAT November 2013 to November 2018]. Cardiovascular health: Insomnia linked to greater risk of heart attack. Venofer injection contains iron sucrose, a form of the mineral iron. Venofer is for use in adults and children at least 2 years old. Canada residents can call a provincial poison control center. Possibleside effectsareweight gainand suicidal thoughts. endobj These are not all of the side effects that may occur. These include: Note: For more information about the potential negative effects of Injectafer, see the Injectafer side effects section above. Or your doctor may recommend that you change your eating habits to include more iron in your diet. Injectafer and Venofer are both brand-name drugs. But its important to note that these studies werent designed to show whether Injectafer is safe to use during pregnancy. Side effects: DayQuil can cause side effects such as drowsiness, dizziness, nausea, vomiting, and stomach upset. If a person does not have an allergic response or any other unanticipated reactions, a doctor will administer the remaining iron. Constipation,dry mouth, headaches, upset stomach, and many othercommonside effectscan greatly affect peoples quality of life, though. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Venofer 100 mg iron/5 mL intravenous solution, Venofer 50 mg iron/2.5 mL intravenous solution, Venofer 200 mg iron/10 mL intravenous solution, Select a condition to view a list of medication options. And this can affect how well those parts of your body are able to work. If you have diarrhea while youre taking Injectafer, call your doctor. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. This way, if you have an allergic reaction to Injectafer, your healthcare professional can treat your reaction. Also, keep in mind that if your anemia is causing certain symptoms, treatment with Injectafer may help those symptoms go away. For example, some people with anemia have extreme fatigue (lack of energy), which can make it hard for them to exercise. I was surprised too but the Dr said it definitely sounds like a reaction. I had Venofer infusions, 2 rounds now in the span of three years. Be ready to tell or show what was taken, how much, and when it happened. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. It will take about three weeks to feel the effects but your fatigue will disappear and you will feel like a new person. This site is intended for use only by US patients. In this group, after 35 days of treatment: In clinical studies, Injectafer was effective in treating IDA in adults with CKD who didnt require dialysis. These lists dont include all possible side effects. And if you dont have an allergic reaction to your first dose of a drug, its typically safe to assume you wont have an allergic reaction to doses that follow. If you miss an appointment for your Injectafer dose, youll need to call your doctors office. muscle pain. Pain, swelling, or redness at the injection site may occur. And this could lead to weight gain, if they increase their food intake. Learn more about these, as well as the symptoms, diagnosis, and treatments. These effects typically last between 7 and 11 hours. Instead, youll start by receiving just one treatment course of Injectafer. These lists contain examples of serious side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). But they wont receive a total cumulative dose of more than 1,500 mg of Injectafer. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. You will need frequent medical tests to help your doctor determine how long to treat you with Venofer. So you wont pick up this medication from a pharmacy. If you are using this medication at home, learn all preparation and usage instructions from your health care professional.