For example, taking very high doses of vitamin B6 can lead to potentially irreversible nerve damage over time, while taking large amounts of niacin — typically in excess of 2 grams per day — can cause liver damage (3, 4). Water-soluble vitamins are readily excreted from the body and not easily stored in tissues. The best way to get the nutrients you need is by consuming a well-rounded diet. Through, this overdose effect of vitamins rarely happens when consumed through food, but can easily develop when consumed in supplement forms. Here are some side effects related to the overconsumption of fat-soluble vitamins: Although vitamin K has a low potential for toxicity, it can interact with certain medications, such as warfarin and antibiotics (6). Here are the 8 most common signs of vitamin and mineral deficiencies…. It’s best to consult your healthcare provider if have questions regarding proper vitamin dosing. 9 Signs and Symptoms of Vitamin B12 Deficiency. The Office of Dietary Supplements says adverse side effects haven't been reported from taking riboflavin supplements even in doses of 400 milligrams per day for three months. In adults, the recommended dietary allowance (RDA) of vitamin C is … The following water-soluble vitamins have set ULs, as they can cause adverse side effects when taken in high doses: Note that these are side effects that healthy people may experience when taking large doses of these vitamins. You don't have to worry about B vitamin toxicity from eating vitamin B-rich foods, as high-dose supplements are the only way to overdose on vitamins. In many cases, it's okay to take B vitamin supplements as long as you're not consuming mega doses of just one B vitamin (and not other B vitamins). Vitamin B1 (Thiamin) Vitamin B1 doesn't have a UL, meaning it's unlikely you'll get too much of this vitamin from supplements. MedlinePlus says there's no known poisoning that's occurred from taking thiamin supplements, and the University of Maryland Medical Center says consuming supplements in doses of 50 to 100 milligrams daily appears to be safe. Nutrient deficiencies may occur with almost every nutrient, but some are more likely than others. Here are 7 incredibly common nutrient deficiencies. Vitamin B12 doesn't have a tolerable upper intake level, which means toxicity from vitamin B12 isn't too much of a concern. Excess fat-soluble vitamin intake from supplements may cause vitamin levels to build to high levels in the body, which can be toxic and pose a danger to health 2. Vitamin B6 (pyridoxine). Too much selenium could lead to hair loss , gastrointestinal upset, fatigue , and mild nerve damage . When you take too much vitamin B complex or particularly excess of vitamin B12, it can cause shortness of breath, pain and numbness in limbs and increase risk of cardiac problems. Vitamin B12 is an essential nutrient, important in nerve and blood cell health, and most people obtain enough of it in food. Healthline Media does not provide medical advice, diagnosis, or treatment. Vitamin A toxicity may lead to serious complications, such as increased spinal fluid pressure, coma, and potentially fatal organ damage (23). In the prostate cancer study, the participants in the vitamin E group were taking 400 international units (IU) a day for several years, even though the recommended daily allowance of vitamin E is just 22 IU a day. In some cases, the patient develops an allergy towards all the members of vitamin B complex group. Though most supplement bottles provide recommendations regarding how much of a vitamin to take per day, needs can vary from person to person. Mega doses of single B vitamins can result in an imbalance with the other B vitamins, so the University of Maryland Medical Center says taking B complex vitamin supplements (containing all B complex vitamins) is the way to go. While vitamin C (ascorbic acid) is an essential nutrient, it's possible to have too much of it. Most people develop vitamin A toxicity by taking high-dose dietary … Allergic skin reactions have also been reported from high doses of B6 supplements. Studies show the consuming an excessive amount of vitamin B12 may: Increase the risk of cardiovascular events in people with diabetic nephropathy : A study published in JAMA sought to determine whether B vitamin therapy was able to slow the progression of diabetic nephropathy (kidney damage due to diabetes) and prevent vascular complications. Vitamin B12 is an important water-soluble vitamin, and deficiency is common. Taking too much vitamin C through supplements can, however, cause side effects. 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