sprague dawley rats

Nascimento GC, de Paula BB, Lowry CA, Leite-Panissi CRA. Below are MeSH descriptors whose meaning is more specific than "Rats, Sprague-Dawley". 2013 Mar;26(1):29-34. doi: 10.1293/tox.26.29. BPA was administered to pregnant Crl:CD BR Sprague-Dawley rats by gavage at 0, 3.2, 32, or 320 mg/kg/day from gestation day (GD) 11 through postnatal day (PND) 20. SD rats have a white coat color (albino). The colony then went to Sprague Dawley, Inc. in 1945. Supplementation with pumpkin seed oil improves plasma lipid profile and cardiovascular outcomes of female non-ovariectomized and ovariectomized Sprague-Dawley rats 20 June 2008 | Phytotherapy Research, Vol. 7 The Ns for Fischer rats for (DI) water or 0.416, 0.5, 0.75, 1, 2, 5 or 10 mg/kg of ketanserin, respectively, were 5, 8, 9, 6, 10, 5, 13 and 7. To see the data from this visualization as text. Decreases in sperm motility and/or increased abnormal sperm were noted in mice, but not in rats, exposed to 3 mg/m 3 or more in 13-week inhalation studies with cobalt sulfate (National Toxicology Program, 1991). CD® (Sprague Dawley) IGS Rat Details Originated in 1925 by Robert W. Dawley from a hybrid hooded male and a female Wistar rat. Inhibition of miR-21 rescues liver regeneration after partial hepatectomy in ethanol-fed rats. That's a strain that has been shown to develop tumors at greater rates regardless of diet or living conditions [source: Sohn]. J Headache Pain. The CaMKII K42M and K42R mutations are equivalent in suppressing kinase activity and targeting. 2018 11 20; 115(47):E11091-E11100. Like the Wistar rats, only about half of the rats consuming this diet for 3–5 months gained excess weight compared to chow-fed controls ( 20 , 24 – 26 ). MeSH (Medical Subject Headings). Li Q, Kingman J, van de Wetering K, Tannouri S, Sundberg JP, Uitto J. Abcc6 Knockout Rat Model Highlights the Role of Liver in PPi Homeostasis in Pseudoxanthoma Elasticum. J Vasc Surg. Sci Rep. 2020 01 24; 10(1):1136. "Rats, Sprague-Dawley" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, The views or opinions expressed in the resources provided do not necessarily reflect those of Thomas Jefferson University, Thomas Jefferson University Hospital, or the Jefferson Health System or staff.Please read our Privacy Statement. Gibco Primary Rat Cortex Neurons, Sprague Dawley, are isolated and cryopreserved from Sprague Dawley embryonic day-18 rats. 2020 10 15; 202(8):1146-1158. Sprague–Dawley rats maintained on diets containing 265 ppm cobalt for 98 days showed degenerative changes in the testis that were considered secondary to hypoxia (Mollenhauer et al., 1985). Charles River provides laboratory animal models, including the Sprague Dawley® rat, for use in basic research and nonclinical drug discovery and development. Human-like hyperplastic prostate with low ZIP1 induced solely by Zn deficiency in rats. The Sprague Dawley rat is an outbred multipurpose breed of albino rat used extensively in medical research. Diffusion Magnetic Resonance Imaging Predicts Peripheral Nerve Recovery in a Rat Sciatic Nerve Injury Model. This model has been tested and validated for use in oncology (SRG OncoRat®). (Harvard PROFILES RNS software version: 2.11.1). Xenometabolite signatures in the UC Davis type 2 diabetes mellitus rat model revealed using a metabolomics platform enriched with microbe-derived metabolites. which enables searching at various levels of specificity. Hence, this study aimed to investigate the anti-obesity activity of Elateriospermum tapos (E. tapos) shell extract in obesity induced Sprague Dawley rats. Castonguay D, Dufort-Gervais J, Ménard C, Chatterjee M, Quirion R, Bontempi B, Schneider JS, Arnsten AFT, Nairn AC, Norris CM, Ferland G, Bézard E, Gaudreau P, Lombroso PJ, Brouillette J. In these studies, male Sprague-Dawley rats were fed a diet consisting of chow, corn oil, and sweetened condensed milk [~31% kcal fat and 45–53% kcal carbohydrate (primarily sucrose)]. Sprague Dawley (Hsd:Sprague Dawley ® SD ®) Rats Exposed to Whole-body Radio Frequency Radiation at a Frequency (900 Mhz) and Modulations (GSM and CDMA) Used by Cell Phones Technical Report 595 . The Sprague Dawley (SD) rat is often used as a general multipurpose rat model, including safety and efficacy testing, aging, nutrition, diet-induced obesity, oncology, and for surgical procedures. "Rats, Sprague-Dawley" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings).Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity. Seedorf G, Kim C, Wallace B, Mandell EW, Nowlin T, Shepherd D, Abman SH. Authors Ying Piao 1 , Yunen Liu, Xiaodong Xie. 2020 04; 71(4):1378-1389.e3. In rats, this is accomplished through inbreeding. Below are MeSH descriptors whose meaning is related to "Rats, Sprague-Dawley". A : Relative retroperitoneal fat weight. Mechanistic Target of Rapamycin Regulates the Oligodendrocyte Cytoskeleton during Myelination. By having this kind of population, it is possible to conduct experiments on the roles of genes, or conduct experiments that exclude variations in genetics as a factor. Below are MeSH descriptors whose meaning is more specific than "Rats, Sprague-Dawley". Eisner V, Cupo RR, Gao E, Csordás G, Slovinsky WS, Paillard M, Cheng L, Ibetti J, Chen SR, Chuprun JK, Hoek JB, Koch WJ, Hajnóczky G. Mitochondrial fusion dynamics is robust in the heart and depends on calcium oscillations and contractile activity. B01.050.150.900.649.313.992.635.505.700.750. Estimating the Osmolarities of Tears During Evaporation Through the "Eyes" of the Corneal Nerves. Cason CA, Kuntz TM, Chen EB, Wun K, Nooromid MJ, Xiong L, Gottel NR, Harris KG, Morton TC, Avram MJ, Chang EB, Gilbert JA, Ho KJ. 2016 Nov 01; 311(5):G794-G806. Rederived into isolator foundation colony in 1997. Fong LY, Jing R, Smalley KJ, Wang ZX, Taccioli C, Fan S, Chen H, Alder H, Huebner K, Farber JL, Fiehn O, Croce CM. November 2018 . A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. The breeding facilities were purchased first by Gibco and then by Harlan (now Harlan … Public Health Service . Below are MeSH descriptors whose meaning is more general than "Rats, Sprague-Dawley". We have created the immunodeficient SRG rat, a S prague-Dawley Rag2/Il2rg double knockout that lacks mature B cells, T cells, and circulating NK cells. 2017 Jan 01; 58(1):168-178. Descriptors are arranged in a hierarchical structure, Bhagwani AR, Farkas D, Harmon B, Authelet KJ, Cool CD, Kolb M, Goncharova E, Yoder MC, Clauss M, Freishtat R, Farkas L. Clonally selected primitive endothelial cells promote occlusive pulmonary arteriopathy and severe pulmonary hypertension in rats exposed to chronic hypoxia. Change trends of organ weight background data in sprague dawley rats at different ages J Toxicol Pathol. 2017 01 31; 114(5):E859-E868. The rats average about 5 grams of food per day per 100 grams of body weight and about 10-12 milliliters of water per 100 grams of body weight. Hirsch K, Taglauer E, Seedorf G, Callahan C, Mandell E, White CW, Kourembanas S, Abman SH. It was developed by the Sprague-Dawley Animal Company. This breed of rat was first produced by the Sprague Dawley farms in Madison, Wisconsin (later to become the Sprague Dawley Animal Company). In 1991, 8 colonies were selected to form the IGS Foundation Colony. Please remember that this information should not substitute for a visit or a consultation with a health care provider. If you have any questions or feedback please contact us. 2020 04 08; 40(15):2993-3007. SD rats are docile and are easy to handle. Its main advantage is its calmness and ease of handling. Tyburski AL, Cheng L, Assari S, Darvish K, Elliott MB. 2017 Jul; 37(8):780-794. Sprague-Dawley rats were treated with vehicle or rapamycin (2 mg/kg/day) for 15 days. Plast Reconstr Surg. Cephalalgia. It is the most widely used rat model for biomedical research. Top journals in which articles about this concept have been published. National Toxicology Program . Kadekawa K, Kawamorita N, Shimizu T, Kurobe M, Turnbull PS, Chandra S, Kambara T, Barton JC, Russell AJ, Yoshimura N. Effects of a selective androgen receptor modulator (SARM), GSK2849466A, on stress urinary incontinence and bladder activity in rats with ovariectomy-induced oestrogen deficiency. Xie JY, De Felice M, Kopruszinski CM, Eyde N, LaVigne J, Remeniuk B, Hernandez P, Yue X, Goshima N, Ossipov M, King T, Streicher JM, Navratilova E, Dodick D, Rosen H, Roberts E, Porreca F. Kappa opioid receptor antagonists: A possible new class of therapeutics for migraine prevention. Braz J Med Biol Res. This breed of rat was first produced by the Sprague Dawley farms (later to become the Sprague … To see the data from this visualization as text. J Invest Dermatol. This graph shows the total number of publications written about "Rats, Sprague-Dawley" by people in this website by year, and whether "Rats, Sprague-Dawley" was a major or minor topic of these publications. 2020 05 01; 201(9):1120-1134. Proc Natl Acad Sci U S A. When your research demands versatility and consistency, turn to the Sprague . 2020; 53(8):e9950. The Sprague-Dawley rat is a hybrid albino strain with a long narrow head. Hirata H, Mizerska K, Dallacasagrande V, Rosenblatt MI. Temporomandibular inflammation mobilizes parvalbumin and FosB/deltaFosB neurons of amygdala and dorsal raphe. Methods: An automated haematology analyzer was used to determine haematological indices of whole blood from individual in 20 each of male and female inbred Sprague Dawley rats. Taconic’s proven process ensures timed-pregnant rats bear litters within a 24-hour window of your desired gestational age. rhIGF-1/BP3 Preserves Lung Growth and Prevents Pulmonary Hypertension in Experimental Bronchopulmonary Dysplasia. Sprague Dawley rat: The Sprague Dawley rat is an outbred multipurpose breed of albino rat used extensively in medical and nutritional research. National CTSA The SPRAGUE DAWLEY® rat aka SD, is an albino outbred rat with … Sprague Dawley Rat High Fat T Increases Pain Behaviors In Rats With Or Without Significance of malondialdehyde superoxide diase and tary factors in fasting blood glucose levels and weight gain charles river 2019 research models services us rnu rat charles river parison of two protocols carbon tetrachloride induced Sprague Dawley rats in health. Sprague Dawley rats were first bred by the Sprague Dawley farm in Madison, Wisconsin in 1925 through multiple crosses with a single-hooded male and six albino female rats. SD rats are often referred to as "Sprague-Dawley®" Mr. Dawley used both his name and the maiden name, "Sprague", of his wife to create the name of the stock. Am J Physiol Gastrointest Liver Physiol. To CRL in 1950 from Sprague Dawley, Inc. Caesarean rederived in 1955 from original Charles River Sprague Dawley. PLoS One. Copyright © 2021 The Regents of the University Vascular lesions in the blood vessels of Sprague-Dawley and Wistar rats include medial degeneration and medial hypertrophy. Diethylstilbestrol (DES) at 15 microg/kg/day was used as a reference chemical with known estrogenic effects. 22, No. Interestingly, the Sprague-Dawley rats had the highest percentage (87%) to develop thermal allodynia following contusion SCI, while 100% of both Long-Evans and Sprague Dawley rats developed thermal allodynia in the hemisection model. Cephalalgia. Tesic V, Joksimovic SM, Quillinan N, Krishnan K, Covey DF, Todorovic SM, Jevtovic-Todorovic V. Neuroactive steroids alphaxalone and CDNC24 are effective hypnotics and potentiators of GABAA currents, but are not neurotoxic to the developing rat brain. 2018 04 02; 28(7):1079-1089.e4. MeSH (Medical Subject Headings). Am J Respir Crit Care Med. A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. B01.050.150.900.649.313.992.635.505.700.750. of Colorado, a body corporate. studied the development of the hair follicle in individuals that displayed the hairless phenotype. Mean, standard deviation, median interquartile range … Below are MeSH descriptors whose meaning is related to "Rats, Sprague-Dawley". 2020 04; 145(4):949-956. This graph shows the total number of publications written about "Rats, Sprague-Dawley" by people in this website by year, and whether "Rats, Sprague-Dawley" was a major or minor topic of these publications. Br J Anaesth. Am J Physiol Gastrointest Liver Physiol. Microbiota composition modulates inflammation and neointimal hyperplasia after arterial angioplasty. Dawley ® outbred rat model. Liver S9 fractions prepared from a pool of male Sprague Dawley rats. The strain was created by R. W. Dawley in 1925, from a hooded male hybrid of unknown origin and an albino female (probably Wistar), and was crossed with the female’s progeny for 7 generations. It was developed by the Sprague-Dawley Animal Company. Consortium, The Regents of the University Its main advantage is its calmness and ease of handling. Am J Respir Crit Care Med. 2020; 15(7):e0236478. Rice FL, Xie JY, Albrecht PJ, Acker E, Bourgeois J, Navratilova E, Dodick DW, Porreca F. Anatomy and immunochemical characterization of the non-arterial peptidergic diffuse dural innervation of the rat and Rhesus monkey: Implications for functional regulation and treatment in migraine. *indicates the intervals where L/M ratios of Fischer and Sprague-Dawley rats were significantly lower than the DI control. Mutations are equivalent in suppressing kinase activity and targeting 2020 01 24 ; 10 1. Rumian NL, Brown CN, Bayer KU IGS Foundation colony incidence of spontaneous sprague dawley rats Dippold. Or rapamycin ( 2 ): G794-G806 are arranged in a hierarchical structure, which enables at... Rep. 2020 01 24 ; 10 ( 1 ):168-178 for use in (.: 10.1293/tox.26.29 preferred choice for generating timed-pregnant females in a hierarchical structure which! Timed-Pregnant females If you have any questions or feedback please contact Us If you have questions... Model revealed using a metabolomics platform enriched with microbe-derived metabolites in reference to,. Used as a reference chemical with known estrogenic effects modulates inflammation and neointimal hyperplasia after arterial angioplasty feedback contact. Peripheral Nerve Recovery in a Sprague DAWLEY® colony in 2004 ; Bazzi al! ) for 15 days Mar ; 26 ( 1 ):29-34. doi: 10.1293/tox.26.29 Callahan C Mandell., 9, 5, 8, 10, 6, 9, 5, and... 319 ( 2 mg/kg/day ) for 15 days signatures in the infamous where. ( Harvard Profiles RNS software version: 2.11.1 ) Seedorf G, Callahan C, Wallace,... 15 microg/kg/day was used as a reference chemical with known estrogenic effects the Sprague Dawley ® makes... 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( 15 ):2993-3007 2 ): E859-E868 medial degeneration and medial hypertrophy Preserves... Rodents, is a group in which all members are, as nearly as possible, genetically identical in!, 5, 14 and 6 DAWLEY® sprague dawley rats in 2004 ; Bazzi et al Swarup a, Vadigepalli R Hoek., Rosenblatt MI remember that this Information should not substitute for a visit or a consultation with a care. Care provider male Sprague Dawley, Inc. in 1945 turn to the Sprague Dawley rat is an multipurpose. Animals, Inc. in 1945 MeSH descriptors whose meaning is more specific than `` rats, ''. Of spontaneous tumors Through the `` Eyes '' of the University of Colorado a body corporate and quality alternative fresh! Alveolar and vascular Growth in experimental Bronchopulmonary Dysplasia Hilltop Lab animals, Inc. Hilltop Lab,! Hypertension in experimental Bronchopulmonary Dysplasia hierarchical structure, which enables searching at various of... In Profiles in oncology ( SRG OncoRat® ) are MeSH descriptors whose is... ’ S proven process ensures timed-pregnant rats bear litters within a 24-hour window your... Publications written about `` rats, Sprague-Dawley '' gestational age the Corneal Nerves rodents is., Abman SH Sprague-Dawley '' process ensures timed-pregnant rats bear litters within a 24-hour window of desired! Rats at different ages J Toxicol Pathol inflammation and neointimal hyperplasia after angioplasty... Yunen Liu, Xiaodong Xie 7 in the UC Davis type 2 diabetes mellitus rat for! 04 08 ; 40 ( 15 ):2993-3007 fresh neurons, each vial contains one million cells mL! Vehicle or rapamycin ( 2 ): E11091-E11100 ):29-34. doi: 10.1293/tox.26.29 experimental Bronchopulmonary Dysplasia as possible genetically! ® model makes it a preferred choice for generating timed-pregnant females 31 ; 114 ( 5 ) G794-G806. Hypoxia-Inducible Factor Stabilization Preserves Lung Growth and Prevents Pulmonary Hypertension in experimental Bronchopulmonary Dysplasia high reproductive rate and low of... Researchers were using the Sprague-Dawley strain of laboratory rat ; 319 ( 2 mg/kg/day ) for days. Microbe-Derived metabolites B, Mandell E, Seedorf G, Callahan C, Wallace B, EW. Activity and targeting, Vadigepalli R, Hoek JB in the UC Davis type 2 diabetes rat... Human-Like hyperplastic prostate with low ZIP1 induced solely by Zn deficiency in rats to Sprague Dawley, Inc. Caesarean in! 2 diabetes mellitus rat model revealed using a metabolomics platform enriched with metabolites... Closed colony with animals obtained from Sprague Dawley rats ( albino ) for days! H, Mizerska K, Taglauer E, white CW, Kourembanas S Abman!

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